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B6 100mg with P5P 60 Caps 



Main Applications

Useful in the treatment of high blood pressure, hyperactivity and PMS.

Vitamins B6, B12 and folic acid are all implicated in the reduction of homocysteine-considered a major risk factor for cardiovascular disease.

Vitamin B6 95mg with 5mg P5P

Vitamin B6 (Pyridoxine) helps the body to absorb vitamin B12, and to produce hydrochloric acid and magnesium. It also improves the function of linoleic acid within the body. Vitamin B6 plays an important role as a coenzyme in the breakdown and utilization of carbohydrates, fats and proteins.The release of glycogen from the liver and muscles for energy is made possible by vitamin B6, and this vitamin must also be present for the production of red blood cells and antibodies.Vitamin B6 also helps to convert the amino acid tryptophan to niacin and is required for the synthesis of DNA and RNA.

Vitamin B6 and PMS

Several studies since the early 70s have confirmed the ability of vitamin B6 supplements to relieve the symptoms of PMS (premenstrual syndrome). The active form of the vitamin-pyridoxal-5'-phosphate (P5P)-has been shown to further ameliorate symptoms in women who have difficulty absorbingvitamin B6.

Vitamin B6 and Cardiovascular Disease

For almost five decades, researchers have recognized that vitamin B6 plays a preventive role in heart disease. People whose blood levels of pyridoxal-5'-phosphate are low five times the risk of experiencing a heart attack as people with higher levels. A deficiency of vitamin B6 leads to the accumulation of homocysteine "a metabolite of the amino acid methionine" which is extremely damaging to the cells that form the lining of the arteries. It is the damage to these cells that ultimately causes atherosclerosis. (It has been estimated that elevated homocysteine levels are a causative factor in approximately 10 percent of heart attacks.)Vitamin B6 has also been shown to inhibit platelet aggregation. (Platelets are substances in the blood that clump together forming clots.)

Vitamin B6 and High Blood Pressure

Tying in closely with heart disease, elevated blood pressure is also positively affected by supplementation with vitamin B6. This vitamin appears to influence the nervous system in a manner that reduces blood pressure.

Vitamin B6 and ADHD (Hyperactivity)

When blood serotonin levels are low, it appears that vitamin B6 supplementation may help alleviate ADHD. In one double-blind, crossover study, six children with low serotonin were given 20-30mg/kg per day (500mg 2-3 times daily for 110lb child). The children treated with vitamin B6 was more effective than methylphenidate (Ritalin). The benefit continued into the following placebo period.

A note about P5P

Pyridoxal-5'-Phosphate is the active coenzyme form of pyridoxine (vitamin B6). Sub-normal activity of the enzyme pyridoxal kinase, low levels of zinc or magnesium or impaired membrane transport can cause a deficiency of Pyridoxal-5'-Phosphate. Certain drugs and physiological disorders such as intestinal malabsorption have also been reported to decrease plasma levels of P5P




Manufactured by:Sisu

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Currency CAD
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SISUB6 100mg with P5P 60 Caps CAD6.99 each

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