Each ml contains:
Fresh organic Passion Flower herb tincture (Passiflora incarnata)
Alcohol content = 66% v/v
1 ml = 33 drops

Adults: take 10 drops in a small amount of water, 3 times daily, 15 minutes before meals. Salivate before swallowing.
Children 4-12 years of age: give half the adult dose.

Native to America, Passion Flower owes its name to the resemblance of its flower to the Christ’s crown of thorns. It was exported by the first Spaniards and rapidly spread in regions with warm climates. Passion Flower was known for its sedative, hypnotic, antispasmodic and « anodynes » (analgesic) properties. It was traditionally used for neuralgia, convulsions, tachycardia, insomnia and hysteria.

Actions and pharmacology

Passion Flower’s main chemical components are alkaloids (harmane, harmaline, harmanine, etc.), flavonoids (vitexine, apigenine, luteoline, quercetine, etc.), maltol and ethylmaltol, sterols, etc.
Cyanogen molecules (producing cyanide in certain conditions) were presumably found in Passion Flower. These molecules have only been identified in a few varieties like Passiflora biflora, P. talamancensis, etc., but never in Passiflora incarnata.⁽³⁾

The flavonoid apigenine links with GABA receptors, which could explain part of Passion Flower’s tranquilizing effect. The alkaloids harmanes may inhibit monoamine oxidase, implying possible antidepressant and stimulant effects. Maltol and ethylmaltol may have sedative and anticonvulsant effects. However, there are too few of these molecules to validate these effects.⁽⁵⁾

Like that of many other herbs, Passion Flower’s effectiveness on anxiety and nervousness relies on the synergy of its components.

The German Commission E acknowledges its benefits in cases of: nervous restlessness.⁽⁴⁾

Scientific studies

A placebo-controlled clinical study on 182 patients evaluated the effectiveness of a medicinal herb combination containing Passion Flower. The results indicate a significant effect on anxiety (measured by Hamilton’s anxiety scale).⁽⁶⁾

In an in vivo study, Passion Flower demonstrated tranquilizing and sedative effects as well as a potentializing action on sub-therapeutic dosages of sleeping drugs.⁽⁷⁾

Precautions, contraindications and interactions

Contraindication: known allergy to Passion Flower.

A study mentions a possible uterotonic effect, preventing Passion Flower’s use during pregnancy.⁽¹⁾ Moreover, its traditional use for dysmenorrhea adds another doubt as to its safety during pregnancy.⁽²⁾ Caution is therefore recommended.

Passion Flower is a mild tranquilizer suitable for children.

Therapeutic combinations

ANXIETY and NERVOUSNESS
Avena Complex, Dormeasan^®, St. John’s Wort, Valerian, Passidora, Urticalcin^®

HYPERACTIVITY
Passidora, Urticalcin^®, AVenaforce^®®

INSOMNIA
Dormeasan^®, St. John’s Wort, Valerian, Passidora, AVenaforce^®®

MENTAL FATIGUE
Avena Complex, Geriaforce, Siberian Ginseng

DEPRESSION
Hyperiforce^®, St. John’s Wort, Avena complex, Siberian Ginseng, Geriaforce, Passidora

FATIGUE and STRESS
Avena Complex, AVenaforce^®®, Geriaforce, Siberian Ginseng, Kelpasan^®, St. John’s Wort, Stinging Nettle, Urticalcin^®

BURNOUT, EXHAUSTION, CHRONIC FATIGUE, NEURASTHENIA
Avena Complex, AVenaforce^®®, St. John’s Wort, Urticalcin^®, Siberian Ginseng, Dormeasan^®, Rasayana^® DX