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Have you tried "the original natural progesterone creamŪ?" Thousands of women rely on Pro-GestŪ monthly. Experience life changes with Pro-GestŪ to maintain balance in your life, to help you feel in harmony with your body, and for menstruation and menopause solutions. For over 20 years Pro-GestŪ has been the preferred choice of women of all ages.

The only natural progesterone cream supported by clinical studies!                             Pro-GestŪ

 Pro-GestŪ has been available for over 20 years and is the natural progesterone cream women ask for by name. Health care professionals and leading physicians support its use as it is the only natural progesterone cream supported by clinical studies.*

In a woman’s body the majority of progesterone is secreted by the corpus luteum, which forms in the ovary following ovulation. During the second half of each monthly cycle, from ovulation until menses, progesterone is designed to be the dominant hormone. Not all women produce sufficient amounts of progesterone during the second half of their cycle. Prior to menopause, as ovarian function wanes, cycles frequently occur where a woman does not ovulate (known as an anovulatory cycle). This period leading up to menopause is referred to as "perimenopause." Anovulatory cycles that begin in perimenopause can lead to hormone changes that may result in hot flashes, changes in bleeding patterns, PMS-type symptoms, as well as many other menopausal symptoms. While progesterone levels fall close to zero due to anovulatory cycles at menopause, estrogen levels may only decline to about 40-60% of pre-menopausal levels. Progesterone has a number of important roles relative to menopause. It is the natural balancer to estrogen, as well as being necessary for optimum estrogen utilization. Research over the years has also revealed other vital roles of progesterone on the heart, blood vessels, nerves and brain. Many women find that supplementing with progesterone allows them to achieve a balance once again.

Instructions For Use Massage 1/4 to 1/2 teaspoon of cream into skin twice daily for 21 days. Discontinue for seven days and repeat. Individual needs may vary.

Pro-GestŪ Body Cream has not been tested on animals


How much progesterone is in Pro-GestŪ?

Pro-GestŪ cream is manufactured to contain 450 milligrams (mg) of natural progesterone per ounce (900 mg per two-ounce tube). Each 1/4 tsp contains approximately 20 mg of natural progesterone.

How does a woman use Pro-GestŪ?

Suggested Use: Pro-GestŪ is best used according to your menstrual status.

To apply, measure the cream into the palm of the hand, and rub into the inner arms, inner thighs, abdomen, or chest, rotating the areas where applied. Pro-GestŪ is best applied twice daily. The following are general recommendations that should be confirmed or modified in concert with your health care provider. Please keep in mind these are general recommendations that may need to be adjusted for your specific situation.
Women in their reproductive years: Pro-GestŪ is best used during the second half of the menstrual cycle, for the two weeks prior to menstruation.

Days 1 (first day of bleeding) -13: do not use Pro-GestŪ.
Days 14 - 21: use 1/4 teaspoon of Pro-GestŪ twice a day.
Days 22-28: use 1/4 to 1/2 teaspoon of Pro-GestŪ twice a day.

Women who are perimenopausal (still menstruating, with cycle changes):

Days 1 (first day of bleeding) - 7: do not use Pro-GestŪ.
Days 8-21: use 1/4 teaspoon of Pro-GestŪ twice a day.
Days 22-28: use 1/4 to 1/2 teaspoon of Pro-GestŪ twice a day.

If your period begins early, STOP using the Pro-GestŪ while you are bleeding. Count the first day of bleeding as day one, and begin the cycle again. If your period is late, use the cream for up to 3 weeks (day 28 of your cycle), then take a week off. If your period has not started by the end of the week off, resume use of the cream as described above for days 8-28 or until your period starts. STOP the cream when your period begins. Count the first day of bleeding as day one of your cycle, and begin the cycle over again.

Women who are menopausal or post-menopausal (no longer menstruating): Choose a calendar day (e.g. first day of the month) as day one.

Days 1-7: do not use Pro-GestŪ.
Days 8-30 (or 31): use 1/8 to 1/4 teaspoon of Pro-GestŪ twice a day.
If needed, you may use up to 1/2 teaspoon of Pro-GestŪ twice a day according to the same schedule.

Does progesterone help raise estrogen levels?
There is no evidence that supplementing with natural progesterone will raise estrogen levels in the body. From salivary test results, we know that women using natural progesterone cream do not by and large see an increase in their estrogen levels. We do know that progesterone and estrogen, like many of the hormones in the body, work synergistically. The presence of progesterone sensitizes estrogen receptors in the body, making circulating estrogen levels work better without changing the actual levels of estrogen. Progesterone performs this role with other hormones as well. Since women's bodies have the ability to produce some estrogens after menopause, many women find that supplementation of progesterone is enough, or at least part of the picture for addressing symptoms. For women who are very thin, who have had hysterectomies at a younger age, or have certain risk factors, like high cholesterol or heightened bone loss, some form of estrogen or phytoestrogens may be necessary to completely fulfill their bodies' needs. Keep in mind that the balance of the different hormones is important and should by tailored to the individual.
What's the difference between synthetic progestins and natural progesterone? "Natural" progesterone (also termed USP Progesterone) refers to a single molecular structure that is "bio-identical" to the progesterone molecule that the body makes. Synthetic "progestins" or "progestogens," do not exactly duplicate the body's own progesterone molecule. They mimic the body's progesterone closely enough to bind to progesterone receptor sites and have some progesterone-like effects, but they do not deliver the full range of "messages" that a natural progesterone molecule would. As such, synthetic progestins are not recommended for use during pregnancy; pregnancy requires progesterone. Synthetic progestins will not increase the serum or salivary levels of progesterone. In fact, synthetic progestins may cause a decrease in the body's levels of natural progesterone by blocking the process of progesterone production. In contrast, research studies show that topical (skin) applications of natural progesterone may increase salivary and serum levels of progesterone. Natural progesterone is available through topical applications, oral micronized progesterone, injectable progesterone, vaginal gel, suppositories, and sublingual drops or troches.
What's the difference between wild yam and progesterone? Wild yam, Dioscorea barbasco, is an herb that has been used historically in herbal medicine for women's health. Some of the actions of wild yam include smooth muscle relaxation and a mild diuretic effect. Contrary to some information provided by companies producing wild yam products, wild yam does not convert into progesterone in the body. This conversion can only occur in a laboratory setting. The body may absorb wild yam extract through the skin, which may in turn have some effect on menopausal symptoms, yet research on both oral and topical applications of wild yam extract demonstrate no change in progesterone levels in the body.
What is USP Progesterone? United States Pharmacopoeia (USP) Progesterone simply means progesterone that exactly duplicates the progesterone naturally produced in the body, or "bio-identical" progesterone. The title "USP Progesterone" differentiates natural progesterone from synthetic progestins or progestogens.
Does natural progesterone have any side effects?
Progesterone binds with progesterone receptor sites in the brain and causes a calming effect on the central nervous system. In excessive amounts, progesterone may have a relaxing effect on the brain, and may cause drowsiness. In a very small group of women who are extremely sensitive, progesterone of any kind may aggravate hormonal headaches or PMS symptoms. There are no long-term adverse effects noted for supplemental progesterone in amounts that replicate physiological levels of progesterone in the body.
What is natural progesterone's role in PMS?
There are several different types of PMS recognized. Women who suffer from certain types of PMS may have a relative excess of estrogen, caused by either a low progesterone level or too much estrogen in relation to progesterone. This condition is often termed "estrogen dominance". Common symptoms of estrogen dominance include breast tenderness, bloating, irritability and mood swings. If your PMS is a result of excess estrogen or insufficient progesterone, then supplementing progesterone during the second half of your cycle (from the time of ovulation until menses) may help reduce PMS symptoms.
Will using natural progesterone with oral birth control pills alter their effectiveness?
Using natural progesterone should not alter the effectiveness of oral birth control pills providing you keep taking the oral birth control pills as prescribed. Birth control pills may be progestin only pills (synthetic progestins), or a combination of progestins and estrogen. Adding supplemental progesterone will only increase the progestational effect in the body.

















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